Depression

A Mind of Your Own: The Truth about Depression – new book by Kelly Brogan, MD

March 10, 2016 By Trudy Scott 8 Comments

I’m thrilled to sharing a new book with you!

Dr. Kelly Brogan is one of my heroes in the world of integrative mental health. She is a trailblazer, bold and is not afraid to say it like it is, and has written her first book A Mind of Your Own: The Truth about Depression and How Women Can Heal Their Bodies to Reclaim Their Lives. It is groundbreaking, brave, science-based and offers a truly holistic approach.

If you struggle with depression (or anxiety), you’ll find this book dispels common myths, and gives you the knowledge you need to truly heal.

According to Dr. Brogan, antidepressants not only overpromise and underdeliver, but their use may permanently disable the body’s self-healing potential. We need a new paradigm: the best way to heal the mind is to heal the whole body. I could not agree more!

Here are some snippets from the book:

Depression is merely a symptom, a sign that something is off balance or ill in the body that needs to be remedied.

Women experience more than twice the rate of depression as men, regardless of race or ethnic background. One in four women in their forties and fifties use psychiatric drugs.

Despite what you’ve been led to believe, antidepressants have repeatedly been shown in long-term scientific studies to worsen the course of mental illness –to say nothing of the risks of liver damage, abnormal bleeding, weight gain, sexual dysfunction, and reduced cognitive function that they entail. The dirtiest little secret of all is the fact that antidepressants are among the most difficult drugs to taper from, more so than alcohol and opiates. While you might call it “going through withdrawal,” we medical professionals have been instructed by Big Pharma to call it “discontinuation syndrome,” which is characterized by fiercely debilitating physical and psychological reactions.

I received an advance review copy and it’s a brilliant book! She bravely and humbly shares:

Before I stopped prescribing, I had never once cured a patient. Now people are cured every week in my practice. As I mentioned, my patients are my partners. We collaborate, and they work hard.

And look at these wise words she offers:

when you have a symptom—when you feel cloudy, sad, sore, gassy, weepy, tired, or unnecessarily anxious—bring some wonder to it. Ask why and try to make the connections. Your body’s symptoms are telling you something about equilibrium. Your body is trying to tell you that it has lost balance. Stand back and appreciate the infinite complexity of your organism.

A Mind of Your Own offers a realistic action plan you can use to heal your body, alleviate inflammation, and feel yourself again without a single prescription!

Please share this if you know anyone who is struggling with depression and/or anxiety. Use this link to get a sample chapter from the book: http://kellybroganmd.com/amindofyourown/?ref=35

We all deserve to feel our absolute best every single day!

Fibromyalgia: tryptophan or 5-HTP for anxiety, depression, pain and insomnia

January 29, 2016 By Trudy Scott 39 Comments

Fibromyalgia syndrome is a musculoskeletal pain and fatigue disorder manifested by diffuse myalgia [muscle aches and pain], localized areas of tenderness, fatigue, lowered pain thresholds, and nonrestorative sleep.

This description comes from a paper titled: Fibromyalgia and the serotonin pathway

The paper discusses how low serotonin is often a contributing factor with fibromyalgia and how beneficial tryptophan and/or 5-HTP can be for the anxiety, depression, pain and insomnia we often see in those with classic fibromyalgia:

Evidence from multiple sources support the concept of decreased flux through the serotonin pathway in fibromyalgia patients.

Serotonin substrate supplementation, via L-tryptophan or 5-hydroxytryptophan (5-HTP), has been shown to improve symptoms of depression, anxiety, insomnia and somatic pains in a variety of patient cohorts.

I recently blogged about the effectiveness of 5-HTP being a clinically-effective serotonin precursor and how it improves many of these same symptoms:

Therapeutic administration of 5-HTP has been shown to be effective in treating a wide variety of conditions, including depression, fibromyalgia, binge eating associated with obesity, chronic headaches, and insomnia.

5-HTP improves symptoms of fibromyalgia but can also cause agitation when cortisol is high

An open 90-day study in 50 patients affected by fibromyalgia found benefits with the use of 5-HTP:

When all the clinical variables studied throughout the trial (number of tender points, anxiety, pain intensity, quality of sleep, fatigue) were compared with baseline results, they all showed a significant improvement.

It is concluded that 5-HTP is effective in improving the symptoms of primary fibromyalgia syndrome and that it maintains its efficacy throughout the 90-day period of treatment.

UPDATES March 25, 2022:

Despite the fact that 5-HTP is beneficial for many individuals there is no one-size fits all.

I don’t recommend 5-HTP when a client has elevated cortisol levels because we know that it can raise cortisol levels in certain individuals. This can leave you feeling agitated, cranky, as well as “wired and tired” at the same time. You may be able to relate to this if you’ve ever used 5-HTP to help with anxiety and insomnia and ended up feeling more anxious and more wide-awake despite your exhaustion and need for sleep. You can read more about this here: Does 5-HTP make you “wired-tired” and affect your sleep when cortisol is high?

A tryptophan-enriched diet and a combination tryptophan product for fibromyalgia symptoms

As you can see below, a tryptophan-enriched diet and a combination tryptophan product improved some fibromyalgia symptoms and for some individuals, but we still need to customize protocols.

In this study, Psychological and Sleep Effects of Tryptophan and Magnesium-Enriched Mediterranean Diet in Women with Fibromyalgia, “the intervention group received a Mediterranean diet enriched with high doses of tryptophan and magnesium.” Interestingly, the source of extra tryptophan (60 mg) and magnesium (60 mg) was eating walnuts at breakfast and dinner!

This study concludes that tryptophan and magnesium-enriched Mediterranean diet reduced anxiety symptoms, mood disturbance, eating disorders, and dissatisfaction with body image but did not improve sleep quality in women with fibromyalgia.

The addition of additional tryptophan as a supplement would be the next thing I’d recommend for improving sleep. This would be dosed according to each person’s unique needs and after doing a trial and adjusting as needed.

In another study, Comparison between Acupuncture and Nutraceutical Treatment with Migratens^® in Patients with Fibromyalgia Syndrome: A Prospective Randomized Clinical Trial, the treatment group used product called Migratens^®, a powdered blend of coenzyme Q10, vitamin D, alpha-lipoic acid, magnesium, tryptophan (300mg), niacin, and riboflavin.

It was used twice a day on an empty stomach and dissolved in a glass of water, spaced about 10 hours apart.

The authors report that “Migratens^® treatment shows a statistically significant reduction of pain 1 month after the start of therapy, strengthened after 3 months with maintenance of treatment.” They also noted improvement in quality of life.

Unfortunately, gastrointestinal side-effects (diarrhea, nausea, dyspepsia, constipation, and lack of appetite) were reported by 11% of participants in the treatment group. I’d suspect these side-effects were caused by the ingredients used to make the product slow release.

It’s not surprising that the authors also confirmed “the validity of acupuncture in these patients, as stated by the most recent literature.”

If we suspect low serotonin may be a factor, I have my clients do the following (whether or not they have a fibromyalgia diagnosis):

complete the Amino Acids Mood Questionnaire from The Antianxiety Food Solution and check off their symptoms on the low serotonin section. The rating uses scale of 1-10 with 10 being worst.
review the Amino Acids Precautions and figure out if we can do a trial of 5-HTP or tryptophan
do a trial of the amino acid 5-HTP or tryptophan and observe for improvements in anxiety, depression, pain, insomnia and the other low serotonin symptoms

We are all unique and some people do better on 5-HTP and some do better on tryptophan. I typically start with a tryptophan trial since I’ve seen such great benefits with this amino acid. If that’s not working, we’ll do a 5-HTP trial, always watching for high cortisol as 5-HTP can raise cortisol if it’s already high. In this instance 5-HTP may be too stimulating.

Quality is an important issue when it comes to the amino acids and this is especially the case with tryptophan. I find that the Lidtke brand is the most superior. You can see my amino acid product recommendations here.

If you suspect low levels of serotonin and do not yet have my book, The Antianxiety Food Solution – How the Foods You Eat Can Help You Calm Your Anxious Mind, Improve Your Mood, and End Cravings, I highly recommend getting it and reading it before jumping in and using amino acids on your own so you are knowledgeable. And be sure to share it with the team you or your loved one is working with. Blog posts like this are intended to add value to the chapter on amino acids, which contains detailed information on doses and time of the day for dosing.

If you are a practitioner, join us in The Balancing Neurotransmitters: the Fundamentals program. It’s an opportunity to interact with me and other practitioners who are also using the amino acids.

Do you have a diagnosis of fibromyalgia and have you found benefits with 5-HTP or tryptophan? For your pain? For your sleep? For your anxiety and/or depression?

I’d love to also hear what else has helped with your symptoms?

Feel free to ask your questions here too.

Healthy ME Summit: Overcoming Depression and Anxiety

January 6, 2016 By Trudy Scott 10 Comments

The “Healthy ME Summit: Overcoming Depression and Anxiety” online event starts this week!

You will discover 50 of the brightest and most brilliant minds in the field of mental health and wellness. The interviews are a collection of experts, as well as individuals sharing their inspirational personal experiences. The culmination of both of these points of view provides you with the answers and solutions to your mental health challenges.

It runs January 7-17, 2016. It’s being hosted from Australia so keep this in mind with regards to the time difference.

As with other online summits each day’s interviews will be available for FREE for a period of 24 hours. They will begin at 10 A.M. Australian Eastern Time and end the next day 9.59 A.M. Here’s the link for time conversion:

http://www.timeanddate.com/worldclock/converter.html

And here’s an example of the time difference: January 7^th 10am Australian Eastern Time is January 6^th 3pm Pacific time USA/ 6pm Eastern time USA. If you’re in the USA, this means each day new speakers will air at 3pm Pacific time USA/ 6pm Eastern time USA AND it starts on January 6^th!

I recently shared some snippets from the excellent interview with Carolyn Ledowsky, Naturopath, Herbalist, Nutritionist: MTHFR, Depression & Anxiety (her interview is on day 1). You can read more here:
https://www.everywomanover29.com/blog/mthfr-depression-and-anxiety-with-carolyn-ledowsky/

Here are a few of the other speakers (including yours truly):

Professor Felice Jacka, Principal Research Fellow: Does Junk Food Shrink Your Brain (her interview is on day 5)

A healthy diet looks very different in different countries

Dr. Tom O’Bryan, International Speaker, Educator: How Wheat Harms the Brain (his interview is on day 3)

Every forkful of what you put in your mouth is either inflammatory or anti-inflammatory

Therese Kerr, Author, Speaker, Health Ambassador: Chemicals in Cosmetics to Avoid (her interview is on day 4)

Fat-soluble chemicals are being passed on to the baby through the mother’s breast milk.

Trudy Scott, Author, Nutritionist, Food Mood Expert: Nutritional Solutions for Anxiety (my interview is on day 3)

People with digestive complaints such as IBS, food allergies and food sensitivities, small intestinal bacterial overgrowth and ulcerative colitis frequently suffer from anxiety and depression.

I’m thrilled to be included in this line-up of experts and I cover how to address anxiety (and depression) using targeted amino acids GABA and tryptophan. I also talk about nutrients for the social anxiety condition called pyroluria (in case you haven’t yet heard me present on these topics – if you have, be sure to tune in to other great interviews).

Hope you can join us! You can learn more and register here:
http://overcomingdepressionandanxiety.com/infuisonsoft.php?p=TrudyScott&w=hme

MTHFR, Depression and Anxiety with Carolyn Ledowsky

December 21, 2015 By Trudy Scott 21 Comments

The Healthy ME Summit: Overcoming Depression and Anxiety runs Jan 7-17, 2016. Here are some snippets from the excellent interview with Carolyn Ledowsky, Naturopath, Herbalist, Nutritionist: MTHFR, Depression & Anxiety.

MTHFR is a gene that helps the conversion of folate to the active form. When you eat leafy greens the body goes through many metabolic processes to change the folate to an active folate and this active folate is what we call a methyl group.

It’s this methyl group that acts as a master switch in really important processes in our body… it helps detoxify chemicals and heavy metals, and really importantly it helps us make glutathione (our major antioxidant that protects us from free radical damage), it helps to process hormones and it’s really important in the stress response.

Stress uses up a lot of our methyl groups and some people use up all their methyl groups when they are really stressed. They can turn the stress response on but then they don’t have enough to turn it off so they stay in this hyper-stress state.

If you have a lack of methyfolate or methyl groups then you don’t have enough components to generate neurotransmitters like serotonin and dopamine.

I would say 80% of people with MTHFR who come to our clinic would experience anxiety or depression and for some of them it’s had a huge impact on their lives and they just can’t function.

Carolyn shares some of the early research on folate and depression, psychosis and schizophrenia; how SAMe is the distributor of all these really important methyl groups to every part of the body; the importance of vitamin B12, zinc, vitamin B6 and how elevated homocysteine is neurotoxic and has a massive impact on mood; how the mutations in the COMT gene can make you less able to tolerate methylfolate; why a vegan or vegetarian diet can be a big factor with anxiety and depression.

She also covers pyroluria (and low zinc and low vitamin B6) as well as high copper and infections:

You can actually get a copper toxicity depression (even without pyroluria). You can have high copper with estrogen dominance, low iron, low molybdenum and one of the key strategies is to balance copper and zinc (and look at why zinc is low to start with)

Strep infections can increase excitatory receptor activity, decreasing GABA levels and impairing speech in kids with autism

It’s a really excellent interview and not to be missed!

Here are more details about the Healthy ME Summit: Overcoming Depression and Anxiety, January 7-17, 2016.

You will discover 50 of the brightest and most brilliant minds in the field of mental health and wellness. The interviews are a collection of experts, as well as individuals sharing their inspirational personal experiences. The culmination of both of these points of view provides you the listener with the answers and solutions to your mental health challenges.

Here are a few of the other excellent speakers and topics:

Nicole Bijlsma, Author, Naturopath, Acupuncturist: Mould The New Asbestos [this is the Australian spelling of mold]
Therese Kerr, Author, Speaker, Health Ambassador: Chemicals in Cosmetics to Avoid
Amy Myers, MD, Author: The Autoimmune Solution for Mental Health
Reed Davis, Functional Nutritionist: Addressing Metabolic Chaos

I’m thrilled to be included in this line-up of experts and I’ll be sharing Nutritional Solutions for Anxiety – and will cover the amino acids GABA and tryptophan, and the social anxiety condition pyroluria.

Hope you can join us! You can learn more and register here:
http://overcomingdepressionandanxiety.com/infuisonsoft.php?p=TrudyScott&w=hme

Anxiety and stress research summary: mother’s age, coffee and benzodiazepines

November 20, 2015 By Trudy Scott Leave a Comment

coffee-and-cream

I like to keep up with recent research papers and I post new studies on my facebook page each week asking for feedback, results, opinions and more. I’ve decided to try something new and I’ve gathered a few of the hot topics into a blog to share here.

Here are a few recent studies and links to the facebook discussions:

(1) Mother’s age at birth may influence symptoms of depression in daughters. Father’s age not a factor; effect not seen in sons, study says

Daughters whose mothers were age 30 to 34 when they gave birth reported significantly higher levels of stress and those whose mothers were over age 35 at the time of birth had significantly higher levels of stress, depression and anxiety compared with daughters whose mothers were under age 30.

Is this true for you, your daughters, your family? It’s not for me. My mom was under 30 when she had me and I really have to watch my stress levels and I did have really bad anxiety in my late 30s. Here is the link to the feedback on the facebook post and as you can see it’s about half and half.

(2) Drink To Your Health: Study Links Daily Coffee Habit To Longevity

In our study, we found people who drank three to five cups of coffee per day had about a 15 percent lower [risk of premature] mortality compared to people who didn’t drink coffee

Based on the all the excited and happy comments in this thread on the NPR facebook page there are many coffee addicts all self-medicating with caffeine! Sorry, but it’s the truth and one of the toughest things for most of my clients to quit.

Unfortunately coffee is not a great choice and it affects so many people with increasing anxiety and panic attacks, causing insomnia, impacting the adrenals and hormones. It’s also dehydrating, affects blood sugar levels, is loaded with pesticides unless organic, can cross-react with gluten and can be a source of mold.

Are you a coffee addict and would you like to quit? Are you a coffee addict but don’t plan to quit? Have you quit and are so glad you did? And what do you drink now? I quit about 18 years ago and I vote for rooibos herbal tea or carob!

Here is the link to the feedback on the facebook post and as you can see most commenters have embraced a life with no coffee which is wonderful!

(3) Drug driving: Are your meds affecting you?

In Australia, drivers with Benzodiazepines (used to treat sleep and anxiety disorders) levels at therapeutic concentrations and higher, were more likely to be culpable in a crash.

Many drivers think that the impairing effects of medicines only occur when they are used excessively, or taken in excess, but that is not the case.by drugs, according to (QUT) Queensland University of Technology road safety researcher Dr Tanya Smyth.

She said driving while affected by prescription and over-the-counter medications had the potential to be as dangerous as driving under the influence of illegal drugs.

The biggest problem is that research has shown drivers are unable to accurately self-assess their impairment when taking medication and are overconfident in assessing their abilities.

The concern is that drivers may be assessing themselves as safe to drive, when in fact they are not.

Many drivers think that the impairing effects of medicines only occur when they are used excessively, or taken in excess, but that is not the case.

Drug Driving is an interesting term and this is very scary considering how many people are prescribed benzodiazepines! If you’re currently on a benzo, do you feel safe driving? If you took benzos in the past, did you feel safe driving? Do you think we need better guidelines for driving for folks on certain prescription medications?

Here is the link to the feedback on the facebook post

I’d love to hear what you think of this format and if this is of interest to you? I’d also like to invite you to come on over to facebook and join in the discussion. Or feel free to post questions and comments right here on the blog.

Western diet is associated with a smaller left hippocampus and anxiety

October 23, 2015 By Trudy Scott Leave a Comment

western-diet

A new food and mental health study has been published in the international BMC Medicine journal: Western diet is associated with a smaller hippocampus: a longitudinal investigation. The lead author is Associate Professor Felice Jacka from Deacon University in Australia.

Here is the conclusion of the study:

Lower intakes of nutrient-dense foods and higher intakes of unhealthy foods are each independently associated with smaller left hippocampal volume. To our knowledge, this is the first human study to demonstrate associations between diet and hippocampal volume concordant with data previously observed in animal models.

Study participants were Australian adults aged 60-64. The results of the study, show that an unhealthy “Western” diet is associated with a smaller left hippocampus and a healthier “prudent”, nutrient-dense diet is associated with a larger left hippocampus.

The unhealthy “Western” diet was:

characterized by the consumption of roast meat, sausages, hamburgers, steak, chips, crisps and soft drinks

and the healthy “prudent”, nutrient-dense diet was:

characterized by the consumption of fresh vegetables, salad, fruit and grilled fish

This study has importance for cognition and mental health, both depression and very possibly anxiety too:

extensive evidence from animal studies points to the importance of the hippocampus in the association between diet and mental and cognitive health

The hippocampus is a brain structure associated with both learning and memory, as well as mood regulation, and is specifically implicated in depression

The study does group high sugar and high saturated fat together, and unfortunately the healthy diet excludes good quality red meat which is surprising considering previous research and conversations with Dr. Jacka about the benefits of good quality red meat and mental health:

In our study, out of every single dietary food grouping that I looked at including vegetables, fruits, salads, beans, etc the strongest correlate of mental health was red meat intake [grass-fed red meat of course]
Consistently, women who have less than the recommended intake of red meat seem to be in an increased risk for common mental disorders [like anxiety and depression] and bipolar disorder.

It will be wonderful to see follow-up research looking at the effect of quality grass-fed red meat on hippocampus size.

Drew Ramsey, MD, an assistant clinical professor of psychiatry at Columbia University College of Physicians and Surgeons in New York City, described the study as “exciting” in an interview on Medscape Medical News:

It’s the first time that a dietary pattern has been linked to specific changes in the brain. We’ve known for a long time that there’s a correlation between dietary pattern and the risk of a number of brain illnesses, like depression and dementia, and the mechanism behind this, we believe, involves neuroplastic processes of how food affects brain growth. This is the first study that’s really shown that quite conclusively.

Dr. Ramsey is the author of The Happiness Diet, and co-founder of National Kale Day. His mission is to educate America on eating healthier and I’ll second what he said about this study:

nutrition should be incorporated into mental health clinical practice.

How wonderful is it to hear a statement like this from a psychiatrist!?

You can read the complete study here.

What does all this mean for you? Eat real whole nutrient-dense food and ditch the junk food and processed food. Your brain will be happy and so will you be!

If you’re a mental health practitioner, start talking to your clients and patients about what they’re eating, ask them what they had for breakfast and share this research.