Today I’m sharing some highlights from a recent eye-opening article in the Washington Post: A catatonic woman awakened after 20 years. Her story may change psychiatry
Before she became a patient, April had been an outgoing, straight-A student majoring in accounting at the University of Maryland Eastern Shore. But after a traumatic event when she was 21, April suddenly developed psychosis and became lost in a constant state of visual and auditory hallucinations. The former high school valedictorian could no longer communicate, bathe or take care of herself.
April was diagnosed with a severe form of schizophrenia
April was hospitalized, medicated and eventually institutionalized. It got to the point where she no longer recognized her family and she became catatonic, “unmoving, unblinking and unknowing of where or who she was.”
Twenty years after April’s original diagnosis it was discovered that she has an autoimmune condition. Dr. Sander Markx is director of precision psychiatry at Columbia University and I have so much admiration for his dedication to the field and the fact that he facilitated this testing and discovery so long after meeting April, when he was a student:
Markx and his colleagues discovered that although April’s illness was clinically indistinguishable from schizophrenia, she also had lupus, an underlying and treatable autoimmune condition that was attacking her brain.
After months of targeted treatments – and more than two decades trapped in her mind – April woke up.
April’s transformation is truly heartwarming and it’s wonderful that the doctors plan to do similar testing and offer similar treatments for others living with schizophrenia who are in mental health institutions in New York State.
Researchers in other countries are making similar connections and it’s really exciting to read that they are recognizing that “underlying autoimmune and inflammatory processes may be more common in patients with a variety of psychiatric syndromes than previously believed.”
We can and should be doing better when looking for root causes
I believe we can and should be doing better when it comes to looking for root causes. Many individuals may have an autoimmune/inflammatory condition and many may have other root cause/s. If I was on an advisory panel these would be my recommendations:
- Use this powerful outcome to really turn psychiatry on its head and screen for lupus and other autoimmune conditions in every single person with schizophrenia. Dr. Markx “believes highly sensitive and inexpensive blood tests to detect different antibodies should become part of the standard screening protocol for psychosis.”
- Do the same for every single person with mental illnesses and illnesses with a behavioral aspect – including anxiety, depression, bipolar, OCD/obsessive compulsive disorder. ADD/ADHD, autism/ASD (autism spectrum disorders), developmental disorders and neurological disorders.
- Go beyond autoimmune screening and do a comprehensive functional medicine and nutritional deficiency assessment for every single person, including low serotonin, low GABA, low vitamin D, low zinc, low vitamin B6, hormone imbalances (sex hormones, adrenals, thyroid health), gut health, liver health etc. This includes testing for infections (such as Lyme and strep), looking at toxin exposure (phthalates, mold, heavy metals) and medication side effects.
If you’re new to the concept of root causes and functional medicine/nutritional testing these two blogs will be helpful. They are specific to anxiety because I work with anxious individuals but much of it can also be applied to other mental health and even physical health conditions (like rheumatoid arthritis and say multiple sclerosis):
- Nutritional testing for figuring out the root cause/s of your anxiety
- 60+ Nutritional & Biochemical Causes of Anxiety
Functional medicine and nutrition for maintaining symptom resolution in the long term
As you read in the article, April received “short, but powerful “pulses” of intravenous steroids for five days, plus a single dose of cyclophosphamide, a heavy-duty immunosuppressive drug typically used in chemotherapy and borrowed from the field of oncology. She was also treated with rituximab, a drug initially developed for lymphoma.”
Incredibly, she recovered completely and was eventually discharged from the psychiatric hospital and has been living in a rehab center for 3 years. Unfortunately “she has recently regressed because she was not receiving adequate maintenance care.”
I see the next step for April and others like her, is maintaining resolution of symptoms in the long term. This is where functional medicine and nutrition shines.
The ISNPR shared this about Nutritional psychiatry in 2015 in a letter published in World Psychiatry, the official journal of the World Psychiatric Association:
In addition to dietary modification, we recognize that nutrient-based (nutraceutical) prescription has the potential to assist in the management of mental disorders at the individual and population level.
In other words, diet and nutrient-based approaches need to be included for mental health treatment and for prevention. One of many examples is the ketogenic diet which has been shown to reduce auditory hallucinations and delusions in those with schizophrenia. Another is the low carb diet helping to reduce bizarre intrusive thoughts. And the SMILES trial was the first randomized controlled trial to show that dietary improvement can actually treat depression.
Specific nutrients can be very powerful too. One example is a case where a woman in my community experienced a drastic reduction in intrusive thoughts, anxiety and fears (and better sleep) with GABA, tryptophan, 5-HTP and the pyroluria protocol (zinc, vitamin B6 and evening primrose oil). More on the blog. Intrusive thoughts can be alleviated with a similar combination of nutrients and by addressing hormonal imbalances too.
These blogs/research illustrate a few of the many root causes of schizophrenia and psychosis other than lupus:
- Case Study: Bartonella and Sudden-Onset Adolescent Schizophrenia
- Toxoplasma gondii: schizophrenia, bipolar disorder, OCD and unresolved anxiety?
-
Gluten sensitivity and relationship to psychiatric symptoms in people with schizophrenia
When it comes to autoimmunity in general I refer you to the work of Dr. Tom O’Bryan, Dr. Izabella Wentz, Dr. Terry Wahls, Dr. Amy Myers and others who teach about using functional medicine and diet for reversing a number of different autoimmune conditions.
The above approaches can all be explored and used when individuals are initially diagnosed too. But keep in mind that there is no one size fits all and it’s a matter of finding the root causes for each person.
We are moving in the right direction and there is hope but…
We are moving in this direction, awareness is growing and there is hope. But I know we can get there sooner.
What Dr. Markx and his colleagues have discovered and shared with the world will hopefully help us get there much more quickly.
(You can read the whole story here and a similar transformation experienced by Devine Cruz.)
I’m thrilled for April and Devine and their families, and appreciate them sharing these stories with the world. Let’s hope their stories do change psychiatry!
Resources if you are new to using amino acids as supplements
If you are new to using amino acids as supplements, here is the Amino Acids Mood Questionnaire from The Antianxiety Food Solution (you can see all the symptoms of neurotransmitter imbalances, including low GABA, low serotonin and low endorphins).
If you suspect low levels of any of the neurotransmitters and do not yet have my book, The Antianxiety Food Solution – How the Foods You Eat Can Help You Calm Your Anxious Mind, Improve Your Mood, and End Cravings, I highly recommend getting it and reading it before jumping in and using amino acids on your own so you are knowledgeable. And be sure to share it with the practitioner/health team you or your loved one is working with.
There is an entire chapter on the amino acids and they are discussed throughout the book in the sections on gut health, gluten, blood sugar control, sugar cravings, anxiety and mood issues.
The book doesn’t include product names (per the publisher’s request) so this blog, The Antianxiety Food Solution Amino Acid and Pyroluria Supplements, lists the amino acids that I use with my individual clients and those in my group programs. You can find them all in my online store.
If, after reading this blog and my book, you don’t feel comfortable figuring things out on your own (i.e. doing the symptoms questionnaire and respective amino acids trials), a good place to get help is the GABA QuickStart Program (if you have low GABA symptoms too). This is a paid online/virtual group program where you get my guidance and community support.
If you are a practitioner, join us in The Balancing Neurotransmitters: the Fundamentals program. This is also a paid online/virtual program with an opportunity to interact with me and other practitioners who are also using the amino acids.
Does this heartwarming story give you hope for psychiatry?
What do you feel we should be doing to advance nutritional psychiatry even more quickly?
Can you or a family member relate to this and what did you discover in terms of testing and nutritional support/functional medicine?
Feel free to post your feedback and questions here in the comments.
Merry Arkose says
Thank you for this article. I am sick of the AMA-dominated Psychiatric Industry that has bamboozled people into thinking they are their diagnosis/label. (e.g. people saying “I am ADHD” “I am Bipolar” instead of saying “I am David” “I am Susan”)
I am with you 100% on objective testing for allergies, auto-immune disorders, nutritional deficiencies, genetic mutations (e.g. MTHFR) and so on.
Psychiatrists are medical doctors and they should be doing this testing first. I read a book a few years ago (A Dose of Sanity was the title I think. I cannot find my book or find it on amazon). The author was a medical doctor and his peers sent him their “untreatable” patients. He found a physical cause for every psych patient sent to him … including diagnoses of syphilis and pinworms!
Trudy Scott says
Merry
Thanks for contributing to the discussion. You raise an excellent point – “Psychiatrists are medical doctors and they should be doing this testing first.” Unfortunately you’ll hear many functional medicine psychiatrists (and other functional medicine practitioners) share that they were never taught this in medical school. Changing this is going to be challenging so incredible stories like this and the nutritional psychiatry research are going to have to be some of the many ways to facilitate change.
Also, educating the public is also key. This way they can advocate for themselves, be empowered with information and challenge their doctors – this is where my work comes in. My book is an excellent starting point – “The Antianxiety Food Solution.” (more here https://www.everywomanover29.com/blog/the-antianxiety-food-solution-by-trudy-scott/) I would love all doctors to read my book too!
I found “A Dose of Sanity” by neuropsychiatrist Dr. Sydney Walker, (my Amazon link https://amzn.to/3NzA5hB) I’m going to try and purchase a copy myself so thanks so much for sharing.
And yes pinworm is notorious for causing many issues including insomnia, hormonal disruption and even PTSD like symptoms. I share a published case study here – A case of enterobiasis presenting as post-traumatic-stress-disorder / PTSD (i.e. a common and parasitic pinworm infection) https://www.everywomanover29.com/blog/a-case-of-enterobiasis-presenting-as-post-traumatic-stress-disorder-ptsd-i-e-a-common-and-parasitic-pinworm-infection/
Jill says
I am so glad I looked at the comments well I almost always go to comments after watching video’s in YT many times the comments are more valuable than the video itself.
I’ve had insomnia for 19 yrs and was put on Ativan and was on that for yrs. About 15-16 yrs! At first it let me get 4 hours sleep At the Most!! But after many yrs it was losing its effect. Well I had to wean myself off of the Ativan and now I take nothing and if I sleep 2 hrs at a time I feel like it’s a miracle but barely sleep thru the night, it’s horrible and I’m 62 yrs old. I live alone and don’t make much money so my options are slim to none.
But You gave me hope when I see you mentioned pinworms can cause insomnia, so now I will read the article you posted and Hope and Pray that may be the solution to my sleep issue’s. Thank you for sharing Trudy ❤️
Debbi Mantooth says
I mistakenly ordered 750mg gaba instead of the orange 125 mg orange sublingual , I’m not sure what to do they aren’t returnable . Will it hurt to cut them into forths ? I have horrible ptsd insomnia for 3 yrs now .
Trudy Scott says
Debbi
I have clients open the 750mg capsule and use the equivalent of 125mg – holding it on their tongue. If they have a hard tablet they can try the same but swallowing 1/5 of a tablet may not work so crushing it is sometimes an option. Often when GABA is swallowed a higher dose works better. With new GABA products it’s a matter of trialing things and seeing which works for each person’s unique needs.
It sounds like 125mg GABA Calm has been working to help your PTSD associated insomnia which is wonderful.
Can you share any insights on how you purchased the 750mg instead as it may help others?
Mary Euphemia Reilly says
This is enlightening and powerful and completely makes sense to me because every human being is “all of a piece” with all of our systems interconnected in ways that are known and unknown. I think the one thing that I am learning is that the food we eat–and supplements–and our gut health play a much bigger role in our immunity and overall health (physical and mental) than anyone ever could have imagined.
If internists and G.P.s don’t “get” functional medicine, it’s hard to expect shrinks to either. Our healthcare system is broken for many reasons, including the limited and hyper-focused on one specialty medical school training that most doctors get with little discussion about nutrition. I always say: “You don’t know what you don’t know” so how can a sleep deprived medical school student know that they are not getting “the big picture?”
And in a healthcare system where, remarkably, testing for Vitamin D levels is not a routine blood test (even after the Covid debacle!), it’s clear that we have to be our own advocates and do our own research now and be persistent enough to try different things to see what will work.
The other challenge is that it has really become a two-tiered healthcare system in the sense that more affluent people have the time and the money to do research and seek out outside-of-the-box treatments. Dr. Hyman has figured this out and did his own hack with the announcement of his new startup Function Health which will attempt to offer normal people extremely comprehensive blood tests at a somewhat affordable price.
Trudy Scott says
Mary
Thanks for sharing your valuable insights and yes to be being our own advocates.
I hear you on the two-tired healthcare system and am thrilled that Dr. Hyman has partnered with Function Health to offer a large array of affordable basic testing and many functional medicine markers too. It’s very empowering for individuals. You say somewhat affordable but if these were done through insurance they would cost thousands (the site states $15,000 vs $499 and I believe this is close.) I feel the challenge may be for some folks to see the value in doing these tests and paying out of pocket.
I see they do offer Antinuclear Antibodies (ANA) so April would have been able to identify lupus. They also offer other autoimmune tests and many more.
Mary Euphemia Reilly says
Thanks for checking out Dr. Mark Hyman’s Function Health website–it’s great to know how comprehensive the offering is. I had not really had a chance to look at it in detail yet. This also may be particularly valuable now for people who think that they may have long-term side effects or illnesses related to having had COVID or from the COVID “vaccine.”